Forxiga® dapagliflozine

Forxiga is een sterk selectieve SGLT2-remmer bij type 2 diabetes, met 4 jaar aan veiligheids- en werkzaamheidsgegevens. Forxiga verwijdert glucose en de bijbehorende calorieën via de nieren.

Referenties

  1. FORXIGA. Samenvatting van de productkenmerken, meest recente versie
  2. XIGDUO. Samenvatting van de productkenmerken, meest recente versie.
  3. IMS Health-database MIDAS, Mei 2017
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  6. Yavin Y, Mansfield TA, Ptaszynska A, Johnsson K, Parikh S, Johnsson E. Effect of the SGLT2 Inhibitor Dapagliflozin on Potassium Levels in Patients with Type 2 Diabetes Mellitus: A Pooled Analysis. Diabetes Ther. 2016;7(1):125-137.
  7. FORXIGA®. Europees openbaar beoordelingsrapport (EPAR), 2012. 2016.
  8. Gegevens uit dossier: Atlas Approval ID: 980,306.011. 2016.
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  21. Frias J, et al. Lancet 2016. E-publicatie voorafgaand aan druk http://dx.doi.org/10.1016/S2213-8587(16)30267-4. 2016.
  22. EMDAC background document. https://www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials/drugs/endocrinologicand-metabolicdrugsadvisorycommittee/ucm378079.pdf. Laatst geraadpleegd in juli 2015.
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  27. Nauck MA, Del Prato S, Meier JJ, et al. Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: a randomized, 52-week, double-blind, active-controlled noninferiority trial. Diabetes Care. 2011;34(9):2015-2022.
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  30. FORXIGA. Voorschrijfinformatie, 2014. 2016.
  31. Jabbour SA, Hardy E, Sugg J, Parikh S. Dapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: a 24-week, multicenter, randomized, double-blind, placebo-controlled study. Diabetes Care. 2014;37(3):740-750.
  32. Matthaei. Matthaei S, et al. Poster 937 gepresenteerd tijdens de 49ste jaarlijkse bijeenkomst van de European Association for the Study of Diabetes (EASD), Barcelona, Spanje, 23–27 september 2013. Poster. 2016.
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  34. Wilding JP, Woo V, Rohwedder K, Sugg J, Parikh S. Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: efficacy and safety over 2 years. Diabetes Obes Metab. 2014;16(2):124-136.
  35. Weber MA, Mansfield TA, Alessi F, Iqbal N, Parikh S, Ptaszynska A. Effects of dapagliflozin on blood pressure in hypertensive diabetic patients on renin-angiotensin system blockade. Blood Press. 2016;25(2):93-103.
  36. Weber MA, Mansfield TA, Cain VA, Iqbal N, Parikh S, Ptaszynska A. Blood pressure and glycaemic effects of dapagliflozin versus placebo in patients with type 2 diabetes on combination antihypertensive therapy: a randomised, double-blind, placebo-controlled, phase 3 study. Lancet Diabetes Endocrinol. 2016;4(3):211-220.
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NS ID BE-1256-RD07/2017-WEB Local code 809